Search on: PTEROYLPOLYGLUTAMIC ACIDS 
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Descriptor English:   Pteroylpolyglutamic Acids 
Descriptor Spanish:   Ácidos Pteroilpoliglutámicos 
Descriptor Portuguese:   Ácidos Pteroilpoliglutâmicos 
Synonyms English:   Folate Polyglutamates
Polyglutamate Folates  
Tree Number:   D03.438.733.631.400.600
Definition English:   Derivatives of folic acid (pteroylglutamic acid). In gamma-glutamyl linkage they are found in many tissues. They are converted to folic acid by the action of pteroylpolyglutamate hydrolase or synthesized from folic acid by the action of folate polyglutamate synthetase. Synthetic pteroylpolyglutamic acids, which are in alpha-glutamyl linkage, are active in bacterial growth assays. 
Indexing Annotation English:   deficiency: coordinate PTEROYLPOLYGLUTAMIC ACIDS /defic (IM) with FOLIC ACID DEFICIENCY (IM)
Pharmacological Action:   Vitamin B Complex
 
History Note English:   91(79); was see under FOLIC ACID 1979-90 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
urine  
Record Number:   27777 
Unique Identifier:   D011624 

Occurrence in VHL:
 

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